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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRN3
All Species:
27.27
Human Site:
Y225
Identified Species:
50
UniProt:
Q9NYV6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYV6
NP_060897.3
651
74107
Y225
S
E
R
T
L
E
C
Y
V
H
N
L
L
R
I
Chimpanzee
Pan troglodytes
XP_001143837
595
67943
G206
D
V
N
A
S
R
Q
G
I
E
D
A
E
E
T
Rhesus Macaque
Macaca mulatta
XP_001108222
651
74080
Y225
S
E
R
T
L
E
C
Y
V
H
N
L
L
R
I
Dog
Lupus familis
XP_536965
651
74211
Y225
S
E
R
T
L
E
C
Y
V
H
N
L
L
R
I
Cat
Felis silvestris
Mouse
Mus musculus
B2RS91
656
74499
Y223
S
E
R
T
L
E
C
Y
V
H
N
L
L
R
I
Rat
Rattus norvegicus
NP_001129318
661
75125
Y223
S
E
R
T
L
E
C
Y
V
H
N
L
L
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518561
660
75690
Y234
S
E
R
T
L
E
C
Y
V
H
N
L
L
R
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001107876
612
69642
E209
Y
F
P
T
L
R
L
E
I
L
E
L
V
V
E
Zebra Danio
Brachydanio rerio
XP_706962
612
68744
D209
Y
I
P
D
L
R
K
D
V
L
E
L
I
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788084
611
70731
Y208
P
Y
H
V
T
A
G
Y
L
Y
N
V
L
W
L
Honey Bee
Apis mellifera
XP_001122533
483
56793
K96
C
M
Q
I
H
Y
A
K
N
V
I
D
N
L
V
Nematode Worm
Caenorhab. elegans
P48322
654
75091
Y212
P
S
V
T
V
A
G
Y
M
R
N
L
I
L
M
Sea Urchin
Strong. purpuratus
XP_784172
374
42533
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
97.6
90.6
N.A.
86.8
85.4
N.A.
76
N.A.
66.8
59.9
N.A.
29.7
27.7
24.4
28.5
Protein Similarity:
100
89
99
94.7
N.A.
92.9
91.8
N.A.
86
N.A.
79.8
76
N.A.
48.8
46.3
42.8
40.7
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
100
N.A.
20
20
N.A.
20
0
26.6
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
N.A.
33.3
26.6
N.A.
46.6
13.3
53.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
16
8
0
0
0
0
8
0
0
0
% A
% Cys:
8
0
0
0
0
0
47
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
8
0
0
8
8
0
0
0
% D
% Glu:
0
47
0
0
0
47
0
8
0
8
16
0
8
8
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
16
8
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
8
0
0
0
0
47
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
0
0
0
16
0
8
0
16
8
47
% I
% Lys:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
62
0
8
0
8
16
0
70
54
16
8
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
8
0
62
0
8
0
0
% N
% Pro:
16
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
47
0
0
24
0
0
0
8
0
0
0
47
0
% R
% Ser:
47
8
0
0
8
0
0
0
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
62
8
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
8
8
8
8
0
0
0
54
8
0
8
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
16
8
0
0
0
8
0
62
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _